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Aspen became the first city in Colorado to enact a law requiring customers to be 21 to purchase tobacco products

Dan Cashman, spokesman for Flavors Hook Kids Maine, a grassroots coalition that is lobbying for the statewide ban and has advocated for the municipal bans, believes the bill has a good chance of passing this year

We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

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Source: Wellcome Collection.